Within a week of switching her to the B12 methylcobalamin her pain started easing and she had energy; prior she was bedridden. It's been 2 years and she's a new person, living everyday with energy and no migraines. We've make other changes like getting her off most of her prescription medications and adding essential supplements like D3, K2-MK7, Magnesium, probiotics,New Chapter Wild Alaskan fish oil, etc, but the 1 biggest difference that practically happened overnight was changing her B12 form to methlycolbalamin.
It was changed my life as well. There's probably other good brands, but we take Neuro Biologix Methylation Complete, because this is the one recommended by my Intergrative MD. It's a sublingual; anyone over 50 can't absorb B12 well from a pill.
Bottle says 2 a day, but blood work reveals only 1 a day gets us in the high optimal range. Hope this helps others. Thanks Harold for sharing your valuable knowledge from clinical experience! I am wondering about the chronic fatigue patients with "normal" B12 levels. Was the testing method inaccurate? I know this is an issue with many nutrients magnesium is an example ; the testing methods are not accurate. What is the best way to measure B12? Perhaps the homocysteine level may be a proxy?
Reply to this post…. I'm looking for information on the safety of B patches. They are not listed in the B reviews. Are they safe? Are they effective? However, there do not appear to be any published, controlled clinical studies demonstrating whether these patches are safe and effective, or comparing the use of these patches to oral B supplementation. Replacement B for gastric disease or or dietary deficiency is one thing.
But when a person needs pharmacologic doses of B along with folate and B-6 to lower dangerous levels of homocysteine, the recommended dietary allowances do not apply.
There should not be a single interpretation for B requirements based on correcting deficiencies. B absorption required for administration of higher amounts of B in people with homocysteine elevation must be considered separately. I would like to see if oral lozenges are better in that other circumstance. More generally, I would like to see Consumerlab.
Hi William - As you note, the recommended daily allowance applies only to maintaining adequate levels of vitamins and minerals, not treating deficiency. Higher amounts are required to treat deficiency, and this is clearly noted in our Reviews. Regarding your interest in lozenges, there does not seem to be any evidence suggesting that these would be a better way to take B vitamins. Thank you. My main interest in making that comment, though, was not in treating deficiencies but in the use of some of the metabolic functions of these nutrients at super "normal" levels to treat other diseases or to prevent diseases not normally associated with a deficiency of that nutrient.
An example would be vitamin D3, which has a very low minimal requirement for bone health, but which requires sometimes ten times as much to achieve its effects at improving insulin sensitivity in diabetes or pre-diabetes or its published positive effects on brain function.
This is what I was referring to with regard to B lowering high levels of artery-damaging blood homocysteine levels. This might require several times more B than is needed to correct deficiencies. This is not to argue a point with your answer, which was fine. It is merely to request additional mention of these things in your answers. There are some situations in which very high doses of nutrients are given. For example, high-dose niacin can lower cholesterol.
High-dose fish oil can lower triglycerides. These are discussed in the relevant Reviews in the "What It Does" section. One needs to be very careful when using high doses -- there are pros and cons. Anything that has an effect probably has a side-effect. For your privacy, only your first name from your account followed by a random number will appear with your comment. Your last name and email address will not be displayed.
All rights reserved. Does not contain egg, milk, peanut, soy, tree nuts, animal products, gluten, lactose or artificial colours, flavours or preservatives. Adults and children over 12 years Dissolve 1 tablet under the tongue, once or twice daily, or as directed by your health professional.
Herbs of Gold Super Calcium Plus with Boron contains calcium and vitamin D plus additional vitamins and minerals to support bone health. Keep up with the latest health news, recipes, new products and exclusive product sales from Herbs of Gold. Magnifying Glass. Left arrow. Active form of vitamin B12 Herbs of Gold Activated Sublingual B12 provides micrograms of co-methylcobalamin, the active form of vitamin B12, in a pleasant tasting tablet that conveniently dissolves under the tongue.
Nervous system health Dissolves under the tongue Active form of vitamin B However, multiple studies have not supported this contention. For B to be absorbed in your intestines, intrinsic factor needs to be secreted by parietal cells in the stomach wall. The release of intrinsic factor is dependent on high acidity and the production of hydrochloric acid. People with deficient hydrochloric acid or intrinsic factor production may benefit the most from sublingual B supplements because they may not be able to absorb any B via the gastrointestinal route.
Another potential advantage of taking sublingual B is affordability. Sublingual B supplements are not appreciably different than oral supplements or intranasal sprays in terms of cost, but they are much less expensive compared to B injections and intravenous B, which must be administered by a health professional. Andrew French graduated from the Canadian Memorial Chiropractic College in and began writing about nutrition shortly thereafter.
By Andrew French Updated December 14,
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